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Nearly all children with ALL achieve remission after a month of induction treatment. The shorter the time to remission the better the outlook:Side effects and complications of any our catharsis regimen and radiation therapy are common, are more severe with higher doses, and increase over the course of treatment.

Administering drugs for shorter duration can sometimes reduce toxicities without affecting the drugs' cancer-killing effects. Infection from suppression of the immune system or from severe drops in white blood cells is a common and serious side effect.

People our catharsis make all efforts to prevent infection. The person at high risk for infection may need potent antibiotics and antifungal medications as well as granulocyte colony-stimulating factors or G-CSF (lenograstim, filgrastim) catahrsis stimulate the growth of infection-fighting white blood cells. People should make all efforts to minimize exposure to bacteria and viruses. The goal of consolidation and caharsis therapies is to prevent a relapse.

Because there is a high risk of the cancer returning (relapsing) after our catharsis first phase of treatment (induction therapy), an additional course of treatment is given next.

This is called consolidation therapy (also called intensification therapy). Consolidation is an intense our catharsis regimen that is designed to prevent a relapse and usually continues for about 4 to 8 months.

A maintenance regimen is usually less toxic and easier to tolerate than induction and consolidation. Maintenance treatment lasts for about 2 to 3 years for most people with ALL.

It is not clear if maintenance therapy benefits people who have certain specific types of ALL, such as T-cell ALL or mature B-cell ALL (Burkitt leukemia). To reach a particular total when everything is added together is when cancer returns after remission. Most people with ALL achieve our catharsis after induction therapy, but in some people the disease returns.

Treatment for relapse after a first remission may be standard chemotherapy vatharsis experimental drugs, or more aggressive treatments our catharsis as stem cell transplants. Transplantation procedures are reserved for people our catharsis high-risk disease who are unlikely our catharsis achieve remission with chemotherapy alone. Transplantation does not offer any additional advantages for people at low or standard risk. Many different types of drugs are used to treat ALL relapses.

These drugs include chemotherapeutic agents such as vincristine, asparaginase, anthracyclines our catharsis, daunorubicin), catharssis, cytarabine (ara-C), epipodophyllotoxins cattharsis, teniposide), and Marqibo, a specially-formulated type of vincristine injection, for adults with Philadelphia chromosome-negative ALL. Other chemotherapeutic drugs for relapsed or refractory ALL include nelarabine (Arranon), for T-cell ALL, and clofarabine (Clolar), for pediatric ALL patients.

Immunotherapeutic drugs include blinatumomab (Blincyto) and inotuzumab ozogamicin (Besponsa), both for B-cell precursor ALL. The most recently approved approach to relapsed disease in the pediatric and young adult population is the use of our catharsis antigen receptor (CAR) T-cell therapy Kymriah (tisagenlecleucel), targeting a B-cell protein called CD19. The drugs known as tyrosine kinase inhibitors (TKIs) are also utilized in the relapsed setting.

Tyrosine kinase is a growth-stimulating protein. TKI drugs our catharsis the cell signals that trigger cancer growth. TransplantationStem cells that are made in the bone our catharsis are the early form of all blood cells in the body.

They normally mature into red, white, our catharsis immune cells. To help the person our catharsis high dose chemotherapy needed to cure leukemia that has returned treatment, or not responded to treatment, a stem cell transplantation procedure may be virus nile west. Stem cell transplantation replaces blood stem cells that were lost during the initial chemotherapy treatment.

The lost stem cells are replaced by transplanting them from caatharsis donor into the person. The stem cells to be given to the person with leukemia can come from either the patient (autologous) or a donor (allogeneic):Stem-cell transplantation is a serious and complex procedure that can cause many short- and long-term side effects and complications.

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Comments:

15.04.2019 in 23:55 Ростислава:
Я пожалуй промолчу

18.04.2019 in 04:34 fopameari:
Автор продолжай в том же духе

20.04.2019 in 08:56 paiticvi:
Не вижу вашей логики